Impact of gut microbiome on child musculoskeletal health and development

In this lecture, Nicolas Bonnet discusses the significant impact of the gut microbiome on child musculoskeletal health, introducing the concept of a "gut musculoskeletal axis." He explains how specific microbiome-driven mechanisms, including the production of short-chain fatty acids, regulation of mineral absorption, and immune modulation, play crucial roles in bone and muscle development during early life. By highlighting findings from a randomized controlled trial, Dr. Bonnet demonstrates impact of consumption of a young child formula containing the synbiotic L. reuteri + GOS on promotion of bone and muscle strength, induction of microbiome changes, supporting bone quality and muscle function improvement in healthy young children.